Improvement of the In Vitro Culture of Echinococcus Granulosus Metacestodes
نویسنده
چکیده
*Corresponding author: María Celina Elissondo, Instituto de Investigaciones en Producción, Sanidad y Ambiente (IIPROSAM) Facultad de Ciencias Exactas y Naturales. Universidad Nacional de Mar del Plata., Funes 3250, 7600-Mar del Plata, Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina. Funes 3250, 7600 Mar del Plata, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina, Tel: +54 223 475 2426; Fax: +54 223 475 3150; Email:
منابع مشابه
In vitro metacestodicidal activities of genistein and other isoflavones against Echinococcus multilocularis and Echinococcus granulosus.
Echinococcus multilocularis and Echinococcus granulosus metacestode infections in humans cause alveolar echinococcosis and cystic echinococcosis, respectively, in which metacestode development in visceral organs often results in particular organ failure. Further, cystic hydatidosis in farm animals causes severe economic losses. Although benzimidazole derivatives such as mebendazole and albendaz...
متن کاملIn vitro effects of nitazoxanide on Echinococcus granulosus protoscoleces and metacestodes.
OBJECTIVES Infection of humans and domestic ruminants with the larval stage (metacestode) of Echinococcus granulosus results in cystic echinococcosis (CE). The metacestode causes a space-occupying lesion in visceral organs, most commonly in the liver. Benzimidazole carbamate derivatives, such as mebendazole and albendazole, are currently used for chemotherapeutic treatment of CE. In human patie...
متن کاملComparative analysis of the 14-3-3 gene and its expression in Echinococcus granulosus and Echinococcus multilocularis metacestodes.
It was suggested that the unlimited proliferative capacity of the Echinococcus multilocularis metacestode may be related to overproduction of the 14-3-3 protein. As is known, the proliferative capacities of E. granulosus and E. multilocularis metacestodes are very different. By comparing the expression levels of the 14-3-3 gene between in vitro-obtained E. granulosus and E. multilocularis metac...
متن کاملIn vitro and in vivo treatments of echinococcus protoscoleces and metacestodes with artemisinin and artemisinin derivatives.
In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 microM) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg of body weight/day) had no effect. However, combination treatments of both drugs with albendazole led ...
متن کاملAnalysis of the Echinococcus granulosus Laminated Layer Carbohydrates by Lectin Blotting
Cystic hydatid disease is caused by cystic larval (metacestode) stages of Echinococcus granulosus. This parasite can potentially occur all over the world especially in Mediterranean and Middle East countries and some parts of Africa, Latin America and China which have major foci of human infections. The cyst wall of metacestodes consists of inner, middle and external layers. To date, little att...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2017